Nodule was firm, mobile, painless and nonulcerated. Abrikossoff definition of abrikossoff by medical dictionary. Granular cell tumor gct, also known as abrikossoff tumor, is an uncommon benign neoplasm, probably of neural origin derived from schwann cells. It develops between the second and sixth decades of life, more frequently among women. Abstract granular cell tumor gct is an uncommon neoplasm of controversial origin that can appear in any corporal localization, including the orofacial region. Abrikossoff tumor or granular cell tumor usually present as unencapsulated, small, firm white mass, usually less than 2 cm with infiltrative borders. Pdf granular cell tumor of the tongue abrikossoffs tumor.
There is a number of theories on their origin under discussion, but the most accepted is the neurogenic theory that covers the neuroectodermal origin of the tumor. The granular cell tumor abrikossoffs tumor in 98% of cases is a. Adjuvant radiation therapy for malignant abrikossoffs. The histogenesis seems to be neural and most likely schwann cell in origin.
Abstract the granular cell tumor abrikossoffs tumor in 98% of cases is a benign neoplasm. Granular cell abrikossoff tumor in the head and neck. Granular cell tumor was described first by abrikossoff in 1926. A very rare entity 1 the first report of granular cell tumor is attributed to abrikossoff in 1926 localized in the tongue and he proposed origin from striated muscle cells and he termed this lesion as myoblastoma. Granular cell tumor is a tumor that can develop on any skin or mucosal surface, but occurs on the tongue 40% of the time it is also known as abrikossoffs tumor, granular cell myoblastoma, granular cell nerve sheath tumor, and granular cell schwannoma. Their presentation is rare and its histological provenience is controversial. More than half of the head and neck lesions are localized to the oral cavity, especially the tongue. The histogenesis of granular cell tumors is unknown. Abstract the granular cell tumor abrikossoff s tumor in 98% of cases is a benign neoplasm. Abrikossoffs tumor or granular cell tumor is a rare soft and usually benign tissue neoplasm of neural origin.
Most common locations are the head and neck, with only a few cases reported on the upper limbs. Total excision using a limberg flap procedure was performed. Abrikossoff s tumor or granular cell tumor is an infrequent benign neoplasm, first described by the russian pathologist abrikossoff in 1926. Abrikossoffs tumor or granular cell tumor is an infrequent benign neoplasm, first described by the russian pathologist abrikossoff in 1926. View research view latest news sign up for updates. Abrikossoffs tumour or granular cell tumour is a rare entity. Abrikossoffs tumor or granular cell tumor gct is usually benign. Granular cell tumor is a tumor that can develop on any skin or mucosal surface, but occurs on the tongue 40% of the time it is also known as abrikossoff s tumor, granular cell myoblastoma, granular cell nerve sheath tumor, and granular cell schwannoma. It might involve multiple anatomical sites, most frequently the head and neck. Pdf granular cell tumor gct, also known as abrikossoffs tumor, is a relatively. Although aggressive and malignant variants of this neoplasm have been described. Some malignant cases have been reported in literature. A 55yearold man with a nodular lesion on the left arm resorted to surgery consultation. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext.
Abrikossoff tumor, otherwise known as myoblastoma or granular cell tumor, occurs more often in women than men, with a ratio of 1. It is now known that their origin is the schwannian cells 6. Granular cell tumor gct, also called abrikossoff tumor, is an unusual, slowly growing neoplasm. Vulvar granular cell tumor abrikossoffs tumor case report. Springer nature is making sarscov2 and covid19 research free. The head and neck areas are affected in 45% to 65% of cases and of these, 70% are located. Abrikossoff s tumor is a disease that more commonly affects the oral cavity but can also occur at other sites. It occurs usually in the neck region or in the head. The neoplasm can affect all parts of the body with head and neck areas affected in 4565% of patients.
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